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Stay away from the concomitant use of strong CYP3A4 inhibitors. Should treatment with any of those agents be need, interrupt therapy with Tasigna. If sufferers has to be coadminister a powerful CYP3A4 inhibitor, lower dosage to 300 mg when daily in individuals with resistant or intolerant Ph+ CML or to 200 mg at the time every day in individuals with recently diagnosed Ph+ CML-CP. nilotinib parkinson

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